منابع مشابه
Esterase activity in erythroleukemia.
Specific esterase activity, a property generally ascribed to cells of granulocytic origin, was found in abnormal erythroid precursors obtained from the bone marrows of six patients with untreated erythroleukemia. These erythroblasts also showed nonspecific esterase activity. Neither specific nor nonspecific esterase activity was detected in erythroid precursors obtained from the bone marrows of...
متن کاملFriend erythroleukemia revisited.
In 1957, Charlotte Friend described a novel retroviral disease in mice characterized by splenic enlargement, erythroleukemia, and death.1 This rapidly progressive disease, now known as Friend disease, has provided a powerful tool for the study of multistage carcinogenesis. Transformed murine erythroleukemia (MEL) cells, isolated from Friend virus–infected mice, have also provided a versatile mo...
متن کاملKey Regulatory Gene Expression in Erythroleukemia Differentiation
The characteristics of cellular and molecular mechanisms associated with cell proliferation and differentiation is important to understand malignancy. In this report we characterise a leukemic model, D5A1, to study the action of differentiation agent, cellular events and gene expression of the selected transcription factors. Cells induced with 4 mM hexamethylene bisacetamide (HMBA) caused signs...
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During normal hematopoietic differentiation, lineage-specific cell surface antigens have been identified in both avian (1) and mammalian (2) species. These differentiation antigens can be found in most cellular compartments of the hematopoietic system and have added a new dimension to the classical morphologic identification of individual cell types during normal differentiation and leukemia. I...
متن کاملKey Regulatory Gene Expression in Erythroleukemia Differentiation
The characteristics of cellular and molecular mechanisms associated with cell proliferation and differentiation is important to understand malignancy. In this report we characterise a leukemic model, D5A1, to study the action of differentiation agent, cellular events and gene expression of the selected transcription factors. Cells induced with 4 mM hexamethylene bisacetamide (HMBA) caused signs...
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ژورنال
عنوان ژورنال: Blood
سال: 1951
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v6.3.261.261